Diane-35 and Acne
Diane 35 is the hormonal control product that I was talking about in my previous posting. It is not available in the US, but there is a newer oral contraceptive containing the progestin drospirenone which is supposedly now available with fewer side effects than Diane 35 / Dianette. The Diane 35 is supposed to be very effective at reducing the negative effects of androgens, which are one of the primary precursors to acne and acne vulgaris, as well as cystic acne. It is the reason that teens get acne so bad, because their hormones are all out of whack when they are younger, and are striving to find a balance.
Androgens tend to dominate the game when you are that young, until your body balances itself out, typically in your mid twenties, then many people who had teen acne tend to find themselves clearing up and drying out a lot more. The Diane 35 pill is actually meant for oral contraception, but it is especially well known for also helping to clear the skin. Typical side effects of the Diane 35 oral contraceptive are about the same as other oral contraceptives, like weight gain, nausea, water retention, etc.
As an acne treatment, Diane-35® works by blocking the effect of androgen on your skin. Receiving no stimulus from androgen, your skin produces less oil, thus reducing the formation of new spots and blackheads. After regular treatment with Diane-35®, your acne usually clears.
The special hormone in Diane-35®, Cyproterone Acetate (CPA), attaches itself to androgen receptors in the skin and then blocks the receptors (“like the wrong key jammed in a lock”) . The androgens then cannot affect the skin. Additionally, as a contraceptive pill, Diane-35® also reduces the activity of the ovaries, so that much smaller amounts of hormones, including acne causing androgens, are produced.
 What you are looking at is a picture of a patient with cystic acne. Cystic acne is a very serious form of acne vulgaris, where cysts form beneath the skin. It is usually very painful, and dermatologists with patients with cystic acne often recommend a very agressive treatment such as accutane. Of course, you know I recommend one of the several natural acne treatments discussed in this magazine, but traditionally these patients are put on accutane.